Styryl-Based and Tricyclic Compounds as Potential Anti-Prion Agents

Prion diseases currently have no effective therapy. These illnesses affect both animal and human populations, and are characterized by the conformational change of a normal self protein PrP(C) (C for cellular) to a pathological and infectious conformer, PrP(Sc) (Sc for scrapie). We used a well chara...

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Detaylı Bibliyografya
Asıl Yazarlar: Chung, Erika, Prelli, Frances, Dealler, Stephen, Lee, Woo Sirl, Chang, Young-Tae, Wisniewski, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172287/
https://ncbi.nlm.nih.gov/pubmed/21931860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024844
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