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Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom’s syndrome gene

Bloom’s syndrome is a human autosomal genetic disorder characterized at the cellular level by genome instability and increased sister chomatid exchanges (SCEs). Clinical features of the disease include proportional dwarfism and a predisposition to develop a wide variety of malignancies. The human BL...

詳細記述

保存先:
書誌詳細
出版年:Genes Dev
主要な著者: Chester, Nicholas, Kuo, Frank, Kozak, Christine, O’Hara, Cathie D., Leder, Philip
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317228/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9808625/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.21.3382
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