Embryonic Lethality in Homozygous Human Her-2 Transgenic Mice Due to Disruption of the Pds5b Gene

The development of antigen-targeted therapeutics is dependent on the preferential expression of tumor-associated antigens (TAA) at targetable levels on the tumor. Tumor-associated antigens can be generated de novo or can arise from altered expression of normal basal proteins, such as the up-regulati...

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Udgivet i:PLoS One
Main Authors: Yong, Carmen S. M., Sharkey, Janelle, Duscio, Belinda, Venville, Ben, Wei, Wei-Zen, Jones, Richard F., Slaney, Clare Y., Mir Arnau, Gisela, Papenfuss, Anthony T., Schröder, Jan, Darcy, Phillip K., Kershaw, Michael H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559457/
https://ncbi.nlm.nih.gov/pubmed/26334628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136817
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