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An active kinase domain is required for retention of PKCθ at the T cell immunological synapse
Protein kinase Cθ (PKCθ) is a serine/threonine kinase that plays an essential role in antigen-regulated responses of T lymphocytes. Upon antigen stimulation, PKCθ is rapidly recruited to the immunological synapse (IS), the region of contact between the T cell and antigen-presenting cell. This behavi...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172272/ https://ncbi.nlm.nih.gov/pubmed/21795397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-11-0916 |
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