HSP70 Mediates Dissociation and Reassociation of the 26S Proteasome During Adaptation to Oxidative Stress

We report an entirely new role for the HSP70 chaperone in dissociating 26S proteasome complexes (into free 20S proteasomes and bound 19S regulators), preserving 19S regulators, and reconstituting 26S proteasomes in the first 1-3 hours following mild oxidative stress. These responses, coupled with di...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Grune, Tilman, Catalgol, Betül, Licht, Anke, Ermak, Gennady, Pickering, Andrew, Ngo, Jenny K., Davies, Kelvin J. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172204/
https://ncbi.nlm.nih.gov/pubmed/21767633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.06.015
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky