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A new regulatory function of the region proximal to the RGG box in the Fragile X mental retardation protein

Fragile X mental retardation protein (FMRP) is required for normal cognition. FMRP has two autosomal paralogs, which although similar to FMRP, cannot compensate for the loss of FMRP expression in brain. The arginine- and glycine-rich region of FMRP (the RGG box) is unique; it is the high-affinity RN...

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Autors principals: Blackwell, Ernest, Ceman, Stephanie
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172185/
https://ncbi.nlm.nih.gov/pubmed/21868366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.086751
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