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A new regulatory function of the region proximal to the RGG box in the Fragile X mental retardation protein

Fragile X mental retardation protein (FMRP) is required for normal cognition. FMRP has two autosomal paralogs, which although similar to FMRP, cannot compensate for the loss of FMRP expression in brain. The arginine- and glycine-rich region of FMRP (the RGG box) is unique; it is the high-affinity RN...

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Detalhes bibliográficos
Main Authors: Blackwell, Ernest, Ceman, Stephanie
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172185/
https://ncbi.nlm.nih.gov/pubmed/21868366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.086751
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