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Arginines of the RGG box regulate FMRP association with polyribosomes and mRNA
Fragile X syndrome is caused by the loss of expression of the fragile X mental retardation protein, FMRP. FMRP is an RNA-binding protein that is highly expressed in neurons and undergoes multiple post-translational modifications including methylation on arginine. FMRP is methylated on the high-affin...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838539/ https://ncbi.nlm.nih.gov/pubmed/20064924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq007 |
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