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p53 and its mutants in tumor cell migration and invasion

In about half of all human cancers, the tumor suppressor p53 protein is either lost or mutated, frequently resulting in the expression of a transcriptionally inactive mutant p53 protein. Loss of p53 function is well known to influence cell cycle checkpoint controls and apoptosis. But it is now clear...

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Bibliografske podrobnosti
Main Authors: Muller, Patricia A. J., Vousden, Karen H., Norman, Jim C.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172183/
https://ncbi.nlm.nih.gov/pubmed/21263025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009059
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