טוען...
Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver
The human drug metabolizing cytochrome P450 (CYP) 1A2, is one of the major P450 isoforms contributing by about 5–20% to the hepatic P450 pool and catalyzing oxidative biotransformation of up to 10% of clinically relevant drugs including clozapine and caffeine. CYP1A2 activity is interindividually hi...
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| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Frontiers Research Foundation
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171976/ https://ncbi.nlm.nih.gov/pubmed/21918647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2010.00129 |
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