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Nedd4-2 Modulates Renal Na(+)-Cl(−) Cotransporter via the Aldosterone-SGK1-Nedd4-2 Pathway
Regulation of renal Na(+) transport is essential for controlling blood pressure, as well as Na(+) and K(+) homeostasis. Aldosterone stimulates Na(+) reabsorption by the Na(+)-Cl(−) cotransporter (NCC) in the distal convoluted tubule (DCT) and by the epithelial Na(+) channel (ENaC) in the late DCT, c...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Nephrology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171941/ https://ncbi.nlm.nih.gov/pubmed/21852580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011020132 |
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