Nedd4-2 Modulates Renal Na(+)-Cl(−) Cotransporter via the Aldosterone-SGK1-Nedd4-2 Pathway

Regulation of renal Na(+) transport is essential for controlling blood pressure, as well as Na(+) and K(+) homeostasis. Aldosterone stimulates Na(+) reabsorption by the Na(+)-Cl(−) cotransporter (NCC) in the distal convoluted tubule (DCT) and by the epithelial Na(+) channel (ENaC) in the late DCT, c...

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Main Authors: Arroyo, Juan Pablo, Lagnaz, Dagmara, Ronzaud, Caroline, Vázquez, Norma, Ko, Benjamin S., Moddes, Lauren, Ruffieux-Daidié, Dorothée, Hausel, Pierrette, Koesters, Robert, Yang, Baoli, Stokes, John B., Hoover, Robert S., Gamba, Gerardo, Staub, Olivier
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2011
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171941/
https://ncbi.nlm.nih.gov/pubmed/21852580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011020132
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