Minimal Residual Disease-Directed Therapy for Childhood Acute Myeloid Leukemia: Results of the AML02 Multicenter Trial

BACKGROUND: We sought to improve outcome of childhood acute myeloid leukemia (AML) by applying risk-directed therapy based on the genetic abnormalities of the leukemic cells and measurements of minimal residual disease (MRD) as determined by flow cytometry during treatment. METHODS: From October 13,...

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Detalhes bibliográficos
Main Authors: Rubnitz, Jeffrey E., Inaba, Hiroto, Dahl, Gary, Ribeiro, Raul C., Bowman, W. Paul, Taub, Jeffrey, Pounds, Stanley, Razzouk, Bassem I, Lacayo, Norman J., Cao, Xueyuan, Meshinchi, Soheil, Degar, Barbara, Airewele, Gladstone, Raimondi, Susana C., Onciu, Mihaela, Coustan-Smith, Elaine, Downing, James R., Leung, Wing, Pui, Ching-Hon, Campana, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171799/
https://ncbi.nlm.nih.gov/pubmed/20451454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(10)70090-5
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