DNA damage activates p53 through a phosphorylation–acetylation cascade

Activation of p53-mediated transcription is a critical cellular response to DNA damage. p53 stability and site-specific DNA-binding activity and, therefore, transcriptional activity, are modulated by post-translational modifications including phosphorylation and acetylation. Here we show that p53 is...

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Bibliografiska uppgifter

I publikationen:	Genes Dev
Huvudupphov:	Sakaguchi, Kazuyasu, Herrera, Julio E., Saito, Shin’ichi, Miki, Toru, Bustin, Michael, Vassilev, Alex, Anderson, Carl W., Appella, Ettore
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Cold Spring Harbor Laboratory Press 1998
Ämnen:	Research Paper
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317174/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9744860/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.18.2831
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