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Inhibition of LuxS by S-Ribosylhomocysteine Analogues Containing a [4-Aza]Ribose Ring
LuxS (S-ribosylhomocysteinase) catalyzes the cleavage of the thioether linkage of S- ribosylhomocysteine (SRH) to produce homocysteine and 4,5-dihydroxy-2,3-pentanedione (DPD), the precursor to a small signaling molecule that mediates interspecies bacterial communication called autoinducer 2 (AI-2)....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171632/ https://ncbi.nlm.nih.gov/pubmed/21855358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.07.043 |
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