Structural basis of inhibition of CDK–cyclin complexes by INK4 inhibitors
The cyclin-dependent kinases 4 and 6 (Cdk4/6) that drive progression through the G(1) phase of the cell cycle play a central role in the control of cell proliferation, and CDK deregulation is a frequent event in cancer. Cdk4/6 are regulated by the D-type cyclins, which bind to CDKs and activate the...
Guardat en:
| Publicat a: | Genes Dev |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2000
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317144/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11124804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.851100 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|