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Fluoroalkyl and Alkyl Chains Have Similar Hydrophobicities in Binding to the “Hydrophobic Wall” of Carbonic Anhydrase
The hydrophobic effect—the free-energetically favorable association of non-polar solutes in water—makes a dominant contribution to binding of many systems of ligands and proteins. The objective of this study was to examine the hydrophobic effect in biomolecular recognition using two chemically diffe...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171206/ https://ncbi.nlm.nih.gov/pubmed/21790183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2045293 |
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