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Dependence of Avidity on Linker Length for a Bivalent Ligand-Bivalent Receptor Model System
This paper describes a synthetic dimer of carbonic anhydrase, and a series of bivalent sulfonamide ligands with different lengths (25 to 69 Å between the ends of the fully extended ligands), as a model system to use in examining the binding of bivalent antibodies to antigens. Assays based on analyti...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272676/ https://ncbi.nlm.nih.gov/pubmed/22088143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2073033 |
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