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Fluoroalkyl and Alkyl Chains Have Similar Hydrophobicities in Binding to the “Hydrophobic Wall” of Carbonic Anhydrase

The hydrophobic effect—the free-energetically favorable association of non-polar solutes in water—makes a dominant contribution to binding of many systems of ligands and proteins. The objective of this study was to examine the hydrophobic effect in biomolecular recognition using two chemically diffe...

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Autors principals: Mecinović, Jasmin, Snyder, Phillip W., Mirica, Katherine A., Bai, Serena, Mack, Eric T., Kwant, Richard L., Moustakas, Demetri T., Heroux, Annie, Whitesides, George M.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171206/
https://ncbi.nlm.nih.gov/pubmed/21790183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2045293
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