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Crucial Points within the Pore as Determinants of K(+) Channel Conductance and Gating
While selective for K(+) ions, K(+) channels vary significantly among their rate of ion permeation. Here we probe the effect of steric hindrance and electrostatics within the ion conduction pathway on K(+) permeation in the MthK K(+) channel using structure-based mutagenesis combined with single cha...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171199/ https://ncbi.nlm.nih.gov/pubmed/21554888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.04.058 |
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