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Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel

The gating ring-forming RCK domain regulates channel gating in response to various cellular chemical stimuli in eukaryotic Slo channel families and the majority of ligand-gated prokaryotic K(+) channels and transporters. Here we present structural and functional studies of a dual RCK-containing, mul...

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Detalhes bibliográficos
Main Authors: Kong, Chunguang, Zeng, Weizhong, Ye, Sheng, Chen, Liping, Sauer, David Bryant, Lam, Yeeling, Derebe, Mehabaw Getahun, Jiang, Youxing
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510474/
https://ncbi.nlm.nih.gov/pubmed/23240087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00184
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