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Zinc sparks are triggered by fertilization and facilitate cell cycle resumption in mammalian eggs

In last few hours of maturation, the mouse oocyte takes up over twenty billion zinc atoms and arrests after the first meiotic division, until fertilization or pharmacological intervention stimulates cell cycle progression towards a new embryo. Using chemical and physical probes, we show that fertili...

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Detalles Bibliográficos
Main Authors: Kim, Alison M., Bernhardt, Miranda L., Kong, Betty Y., Ahn, Richard W., Vogt, Stefan, Woodruff, Teresa K., O’Halloran, Thomas V.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171139/
https://ncbi.nlm.nih.gov/pubmed/21526836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200084y
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