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Zinc sparks are triggered by fertilization and facilitate cell cycle resumption in mammalian eggs
In last few hours of maturation, the mouse oocyte takes up over twenty billion zinc atoms and arrests after the first meiotic division, until fertilization or pharmacological intervention stimulates cell cycle progression towards a new embryo. Using chemical and physical probes, we show that fertili...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171139/ https://ncbi.nlm.nih.gov/pubmed/21526836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200084y |
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