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Zinc sparks are triggered by fertilization and facilitate cell cycle resumption in mammalian eggs

In last few hours of maturation, the mouse oocyte takes up over twenty billion zinc atoms and arrests after the first meiotic division, until fertilization or pharmacological intervention stimulates cell cycle progression towards a new embryo. Using chemical and physical probes, we show that fertili...

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Bibliografische gegevens
Hoofdauteurs: Kim, Alison M., Bernhardt, Miranda L., Kong, Betty Y., Ahn, Richard W., Vogt, Stefan, Woodruff, Teresa K., O’Halloran, Thomas V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171139/
https://ncbi.nlm.nih.gov/pubmed/21526836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200084y
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