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Quantitative mapping of zinc fluxes in the mammalian egg reveals the origin of fertilization-induced zinc sparks

Fertilization of a mammalian egg induces a series of ‘zinc sparks’ that are necessary for inducing the egg-to-embryo transition. Despite the importance of these zinc efflux events little is known about their origin. To understand the molecular mechanism of the zinc spark we combined four physical ap...

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Détails bibliographiques
Publié dans:Nat Chem
Auteurs principaux: Que, Emily L., Bleher, Reiner, Duncan, Francesca E., Kong, Betty Y., Gleber, Sophie C., Vogt, Stefan, Chen, Si, Garwin, Seth A., Bayer, Amanda R., Dravid, Vinayak, Woodruff, Teresa K., O’Halloran, Thomas V.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315321/
https://ncbi.nlm.nih.gov/pubmed/25615666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2133
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