DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity

The c-Jun N-terminal kinase (JNK) signaling pathway is essential for neuronal degeneration in multiple contexts but also regulates neuronal homeostasis. It remains unclear how neurons are able to dissociate proapoptotic JNK signaling from physiological JNK activity. In this paper, we show that the m...

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Autores principales: Ghosh, Arundhati Sengupta, Wang, Bei, Pozniak, Christine D., Chen, Mark, Watts, Ryan J., Lewcock, Joseph W.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171129/
https://ncbi.nlm.nih.gov/pubmed/21893599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201103153
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