DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity

The c-Jun N-terminal kinase (JNK) signaling pathway is essential for neuronal degeneration in multiple contexts but also regulates neuronal homeostasis. It remains unclear how neurons are able to dissociate proapoptotic JNK signaling from physiological JNK activity. In this paper, we show that the m...

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Bibliografiske detaljer
Main Authors: Ghosh, Arundhati Sengupta, Wang, Bei, Pozniak, Christine D., Chen, Mark, Watts, Ryan J., Lewcock, Joseph W.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2011
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171129/
https://ncbi.nlm.nih.gov/pubmed/21893599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201103153
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