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Mechanism for modulation of gating of connexin26-containing channels by taurine
The mechanisms of action of endogenous modulatory ligands of connexin channels are largely unknown. Previous work showed that protonated aminosulfonates (AS), notably taurine, directly and reversibly inhibit homomeric and heteromeric channels that contain Cx26, a widely distributed connexin, but not...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171079/ https://ncbi.nlm.nih.gov/pubmed/21844220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110634 |
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