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Mechanism of gating by calcium in connexin hemichannels

Aberrant opening of nonjunctional connexin hemichannels at the plasma membrane is associated with many diseases, including ischemia and muscular dystrophy. Proper control of hemichannel opening is essential to maintain cell viability and is achieved by physiological levels of extracellular Ca(2+), w...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Lopez, William, Ramachandran, Jayalakshmi, Alsamarah, Abdelaziz, Luo, Yun, Harris, Andrew L., Contreras, Jorge E.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150374/
https://ncbi.nlm.nih.gov/pubmed/27872296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609378113
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