Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules

Cysteine-scanning mutagenesis combined with thiol reagent modification is a powerful method with which to define the pore-lining elements of channels and the changes in structure that accompany channel gating. Using the Xenopus laevis oocyte expression system and two-electrode voltage clamp, we perf...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Tong, Xuhui, Lopez, William, Ramachandran, Jayalakshmi, Ayad, Wafaa A., Liu, Yu, Lopez-Rodriguez, Angelica, Harris, Andrew L., Contreras, Jorge E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Methods and Approaches
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555470/
https://ncbi.nlm.nih.gov/pubmed/26324677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511375
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