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“End-Stage” Neurofibrillary Tangle Pathology in Preclinical Alzheimer's Disease: Fact or Fiction?

Among individuals who were cognitively intact before death, autopsies may reveal some Alzheimer's disease-type pathology. The presence of end-stage pathology in cognitively intact persons would support the hypothesis that pathological markers are epiphenomena. We assessed advanced neurofibrilla...

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Bibliographische Detailangaben
Hauptverfasser: Abner, Erin L., Kryscio, Richard J., Schmitt, Frederick A., SantaCruz, Karen S., Jicha, Gregory A., Lin, Yushun, Neltner, Janna M., Smith, Charles D., Van Eldik, Linda J., Nelson, Peter T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171001/
https://ncbi.nlm.nih.gov/pubmed/21471646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2011-101980
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