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A tick mannose-binding lectin inhibits the vertebrate complement cascade to enhance transmission of the Lyme disease agent

The Lyme disease agent, Borrelia burgdorferi, is primarily transmitted to vertebrates by Ixodes ticks. The classical and alternative complement pathways are important in Borrelia eradication by the vertebrate host. We recently identified a tick salivary protein, designated P8 that reduced complement...

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Bibliografske podrobnosti
Main Authors: Schuijt, Tim J., Coumou, Jeroen, Narasimhan, Sukanya, Dai, Jianfeng, DePonte, Kathleen, Wouters, Diana, Brouwer, Mieke, Oei, Anneke, Roelofs, Joris J.T.H., van Dam, Alje P., van der Poll, Tom, van ’t Veer, Cornelis, Hovius, Joppe W., Fikrig, Erol
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170916/
https://ncbi.nlm.nih.gov/pubmed/21843870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.06.010
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