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Tetraarsenic Hexoxide Induces Beclin-1-Induced Autophagic Cell Death as well as Caspase-Dependent Apoptosis in U937 Human Leukemic Cells

Tetraarsenic hexaoxide (As(4)O(6)) has been used in Korean folk remedy for the treatment of cancer since the late 1980s, and arsenic trioxide (As(2)O(3)) is currently used as a chemotherapeutic agent. However, evidence suggests that As(4)O(6)-induced cell death pathway was different from that of As(...

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Main Authors: Han, Min Ho, Lee, Won Sup, Lu, Jing Nan, Yun, Jeong Won, Kim, GonSup, Jung, Jin Myung, Kim, Gi-Young, Lee, Su-Jae, Kim, Wun-Jae, Choi, Yung Hyun
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170805/
https://ncbi.nlm.nih.gov/pubmed/21912568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/201414
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