Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells

Although tetraarsenic hexoxide is known to exert an anti-tumor effect by inducing apoptosis in various cancer cells, its effect on other forms of regulated cell death remains unclear. Here, we show that tetraarsenic hexoxide induces the pyroptotic cell death through activation of mitochondrial react...

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書誌詳細
出版年:Cell Death Dis
主要な著者: An, Haein, Heo, Jin Sun, Kim, Pyunggang, Lian, Zenglin, Lee, Siyoung, Park, Jinah, Hong, Eunji, Pang, Kyoungwha, Park, Yuna, Ooshima, Akira, Lee, Jihee, Son, Minjung, Park, Hyeyeon, Wu, Zhaoyan, Park, Kyung-Soon, Kim, Seong-Jin, Bae, Illju, Yang, Kyung-Min
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870965/
https://ncbi.nlm.nih.gov/pubmed/33558527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03454-9
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