Tetraarsenic Hexoxide Induces Beclin-1-Induced Autophagic Cell Death as well as Caspase-Dependent Apoptosis in U937 Human Leukemic Cells

Tetraarsenic hexaoxide (As(4)O(6)) has been used in Korean folk remedy for the treatment of cancer since the late 1980s, and arsenic trioxide (As(2)O(3)) is currently used as a chemotherapeutic agent. However, evidence suggests that As(4)O(6)-induced cell death pathway was different from that of As(...

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Bibliographische Detailangaben
Hauptverfasser: Han, Min Ho, Lee, Won Sup, Lu, Jing Nan, Yun, Jeong Won, Kim, GonSup, Jung, Jin Myung, Kim, Gi-Young, Lee, Su-Jae, Kim, Wun-Jae, Choi, Yung Hyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170805/
https://ncbi.nlm.nih.gov/pubmed/21912568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/201414
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