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A phase Ib trial of the combination of the anti-angiogenic agent sunitinib and radiation therapy for patients with primary and metastatic central nervous system malignancies
PURPOSE: This phase I trial evaluated sunitinib combined with radiation therapy (RT) for primary or metastatic central nervous system (CNS) malignancies. EXPERIMENTAL DESIGN: Eligible patients had CNS malignancies requiring a (minimum) two week course of RT. Sunitinib (37.5 mg) was administered dail...
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| Autores principales: | , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3170674/ https://ncbi.nlm.nih.gov/pubmed/21647871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26216 |
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