Ku acts in a unique way at the mammalian telomere to prevent end joining

Telomeres are specialized DNA/protein structures that act as protective caps to prevent end fusion events and to distinguish the chromosome ends from double-strand breaks. We report that TRF1 and Ku form a complex at the telomere. The Ku and TRF1 complex is a specific high-affinity interaction, as d...

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Main Authors: Hsu, Hsin-Ling, Gilley, David, Galande, Sanjeev A., Hande, M. Prakash, Allen, Beth, Kim, Sahn-Ho, Li, Gloria C., Campisi, Judith, Kohwi-Shigematsu, Terumi, Chen, David J.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2000
主題:
Research Communication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC317061/
https://ncbi.nlm.nih.gov/pubmed/11090128
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