Ku acts in a unique way at the mammalian telomere to prevent end joining

Telomeres are specialized DNA/protein structures that act as protective caps to prevent end fusion events and to distinguish the chromosome ends from double-strand breaks. We report that TRF1 and Ku form a complex at the telomere. The Ku and TRF1 complex is a specific high-affinity interaction, as d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hsu, Hsin-Ling, Gilley, David, Galande, Sanjeev A., Hande, M. Prakash, Allen, Beth, Kim, Sahn-Ho, Li, Gloria C., Campisi, Judith, Kohwi-Shigematsu, Terumi, Chen, David J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2000
Pynciau:
Research Communication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC317061/
https://ncbi.nlm.nih.gov/pubmed/11090128
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg