Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

The liver X receptors (LXRs) are members of the nuclear hormone receptor superfamily that are bound and activated by oxysterols. These receptors serve as sterol sensors to regulate the transcription of gene products that control intracellular cholesterol homeostasis through catabolism and transport....

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Autori principali: Repa, Joyce J., Liang, Guosheng, Ou, Jiafu, Bashmakov, Yuriy, Lobaccaro, Jean-Marc A., Shimomura, Iichiro, Shan, Bei, Brown, Michael S., Goldstein, Joseph L., Mangelsdorf, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2000
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC317055/
https://ncbi.nlm.nih.gov/pubmed/11090130
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