Mechanism of AMPK Suppression of LXR-dependent Srebp-1c Transcription
<p>Activation of AMP-activated protein kinase (AMPK) inhibits hepatic fatty acid synthesis by suppressing sterol regulatory element-binding protein (SREBP)-1c, a master regulator of hepatic lipogenic gene expression. Using a model cell line rat hepatoma McA-RH7777 (CRL-1601) that mimics the behavior...
Guardado en:
| Autor principal: | |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Ivyspring International Publisher
2011-01-01
|
| Colección: | International Journal of Biological Sciences |
| Acceso en línea: | http://www.biolsci.org/v07p0645.htm |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|