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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

The liver X receptors (LXRs) are members of the nuclear hormone receptor superfamily that are bound and activated by oxysterols. These receptors serve as sterol sensors to regulate the transcription of gene products that control intracellular cholesterol homeostasis through catabolism and transport....

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Udgivet i:Genes Dev
Principais autores: Repa, Joyce J., Liang, Guosheng, Ou, Jiafu, Bashmakov, Yuriy, Lobaccaro, Jean-Marc A., Shimomura, Iichiro, Shan, Bei, Brown, Michael S., Goldstein, Joseph L., Mangelsdorf, David J.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2000
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317055/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11090130/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.844900
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