Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination

Tumour necrosis factor is linked to the pathophysiology of various neurodegenerative disorders including multiple sclerosis. Tumour necrosis factor exists in two biologically active forms, soluble and transmembrane. Here we show that selective inhibition of soluble tumour necrosis factor is therapeu...

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Bibliographic Details
Main Authors: Brambilla, Roberta, Ashbaugh, Jessica Jopek, Magliozzi, Roberta, Dellarole, Anna, Karmally, Shaffiat, Szymkowski, David E., Bethea, John R.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170538/
https://ncbi.nlm.nih.gov/pubmed/21908877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awr199
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