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Immunogenicity of Therapeutic Proteins: The Use of Animal Models

Immunogenicity of therapeutic proteins lowers patient well-being and drastically increases therapeutic costs. Preventing immunogenicity is an important issue to consider when developing novel therapeutic proteins and applying them in the clinic. Animal models are increasingly used to study immunogen...

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Bibliografiske detaljer
Main Authors: Brinks, Vera, Jiskoot, Wim, Schellekens, Huub
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170476/
https://ncbi.nlm.nih.gov/pubmed/21744171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0523-5
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