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Immunogenicity of Therapeutic Proteins: The Use of Animal Models

Immunogenicity of therapeutic proteins lowers patient well-being and drastically increases therapeutic costs. Preventing immunogenicity is an important issue to consider when developing novel therapeutic proteins and applying them in the clinic. Animal models are increasingly used to study immunogen...

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Detalhes bibliográficos
Main Authors: Brinks, Vera, Jiskoot, Wim, Schellekens, Huub
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170476/
https://ncbi.nlm.nih.gov/pubmed/21744171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0523-5
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