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Slowing the Translocation of Double-Stranded DNA Using a Nanopore Smaller than the Double Helix

It is now possible to slow and trap a single molecule of double-stranded DNA (dsDNA), by stretching it using a solid-state nanopore smaller in diameter than the double helix. By applying an electric force larger than the threshold for stretching, dsDNA can be impelled through the pore. Once a curren...

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Hlavní autoři: Comer, Utkur Mirsaidov Jeffrey, Dimitrov, Valentin, Aksimentiev, Aleksei, Timp, Gregory
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170403/
https://ncbi.nlm.nih.gov/pubmed/20808032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0957-4484/21/39/395501
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