Fra-1 replaces c-Fos-dependent functions in mice

Structure–function analysis as well as studies with knock-out and transgenic mice have assigned distinct functions to c-Fos and Fra-1, two components of the transcription factor AP-1 (activator protein-1). To test whether Fra-1 could substitute for c-Fos, we generated knock-in mice that express Fra-...

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Autors principals: Fleischmann, Alexander, Hafezi, Farhad, Elliott, Candace, Remé, Charlotte E., Rüther, Ulrich, Wagner, Erwin F.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2000
Matèries:
Research Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC317035/
https://ncbi.nlm.nih.gov/pubmed/11069886
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