Sustained productivity in recombinant Chinese Hamster Ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype

BACKGROUND: The ability of mammalian cell lines to sustain cell specific productivity (Qp) over the full duration of bioprocess culture is a highly desirable phenotype, but the molecular basis for sustainable productivity has not been previously investigated in detail. In order to identify proteins...

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Библиографические подробности
Главные авторы: Meleady, Paula, Doolan, Padraig, Henry, Michael, Barron, Niall, Keenan, Joanne, O'Sullivan, Finbar, Clarke, Colin, Gammell, Patrick, Melville, Mark W, Leonard, Mark, Clynes, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170212/
https://ncbi.nlm.nih.gov/pubmed/21781345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-78
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