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Cationic gold(I) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls

It has been established that a cationic gold(I)/(R)-DTBM-Segphos or (R)-BINAP complex catalyzes the atropselective intramolecular hydroarylation of alkynes leading to enantioenriched axially chiral 4-aryl-2-quinolinones and 4-arylcoumarins with up to 61% ee.

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Detalhes bibliográficos
Main Authors: Shibuya, Tetsuro, Nakamura, Kyosuke, Tanaka, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170204/
https://ncbi.nlm.nih.gov/pubmed/21915192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.7.105
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