The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation

Smads regulate transcription of defined genes in response to TGF-β receptor activation, although the mechanisms of Smad-mediated transcription are not well understood. We demonstrate that the TGF-β-inducible Smad3 uses the tumor suppressor Smad4/DPC4 and CBP/p300 as transcriptional coactivators, whi...

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Bibliografske podrobnosti
Main Authors: Feng, Xin-Hua, Zhang, Ying, Wu, Rui-Yun, Derynck, Rik
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1998
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC317015/
https://ncbi.nlm.nih.gov/pubmed/9679060
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