A network biology approach evaluating the anticancer effects of bortezomib identifies SPARC as a therapeutic target in adult T-cell leukemia cells

There is a need to identify the regulatory gene interaction of anticancer drugs on target cancer cells. Whole genome expression profiling offers promise in this regard, but can be complicated by the challenge of identifying the genes affected by hundreds to thousands of genes that induce changes in...

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Hauptverfasser: Ohyashiki, Junko H, Hamamura, Ryoko, Kobayashi, Chiaki, Zhang, Yu, Ohyashiki, Kazuma
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2008
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169936/
https://ncbi.nlm.nih.gov/pubmed/21918608
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