Induction of heme oxygenase-1 by cobalt protoporphyrin enhances the antitumour effect of bortezomib in adult T-cell leukaemia cells

Adult T-cell leukaemia (ATL) is a lethal neoplasia derived from HTLV-1-infected T lymphocytes frequently exhibiting nuclear factor-κB (NF-κB) activation. Despite the use of various treatment regimens, the prognosis of ATL is poor, and new treatment strategies are urgently needed. We therefore explor...

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Detalhes bibliográficos
Main Authors: Hamamura, R S, Ohyashiki, J H, Kurashina, R, Kobayashi, C, Zhang, Y, Takaku, T, Ohyashiki, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360455/
https://ncbi.nlm.nih.gov/pubmed/17895889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604003
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