A network biology approach evaluating the anticancer effects of bortezomib identifies SPARC as a therapeutic target in adult T-cell leukemia cells

There is a need to identify the regulatory gene interaction of anticancer drugs on target cancer cells. Whole genome expression profiling offers promise in this regard, but can be complicated by the challenge of identifying the genes affected by hundreds to thousands of genes that induce changes in...

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Autors principals: Ohyashiki, Junko H, Hamamura, Ryoko, Kobayashi, Chiaki, Zhang, Yu, Ohyashiki, Kazuma
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2008
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169936/
https://ncbi.nlm.nih.gov/pubmed/21918608
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