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The Molecular Origin and Consequences of Escape from miRNA Regulation by HLA-C Alleles

Differential expression of human leukocyte antigen C (HLA-C) allotypes is mediated by the binding of a microRNA, miR-148a, to the 3′ untranslated region of some, but not all, HLA-C alleles. The binding results in lower levels of HLA-C expression, which is associated with higher levels of HIV-1 viral...

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Sonraí Bibleagrafaíochta
Main Authors: O'hUigin, Colm, Kulkarni, Smita, Xu, Yunping, Deng, Zhihui, Kidd, Judith, Kidd, Kenneth, Gao, Xiaojiang, Carrington, Mary
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169826/
https://ncbi.nlm.nih.gov/pubmed/21907013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.07.024
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