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The Ying and Yang of HLA and KIR in Human Disease
Killer cell immunoglobulin-like receptors (KIR) are expressed on natural killer (NK) cells and subsets of T cells. The KIR genes are polymorphic and the KIR gene complex is polygenic with varying numbers of inhibitory and activating receptors. HLA class I molecules serve as ligands for the KIR. Inte...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501819/ https://ncbi.nlm.nih.gov/pubmed/18635379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2008.06.003 |
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